28 results
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
arthritis, Skin rash ... Differential Diaqnoses ... solid cancers • Systemic ... #diagnosis #management ... #treatment #rheumatology
Maculopapular Rashes - THE ALGORITHMIC APPROACH 

The term maculopapule is a portmanteau, a combination
of macule and
and systemic toxicity ... differential diagnosis ... assessed for Lyme disease ... dependent upon systemic ... #Diagnosis #Dermatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... characterized by a systemic ... late stages of disease ... #Diagnosis #Clinical ... #Photo #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... Petechial or purpuric rash ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Manifestations: Malar rash ... Evolution: Chronic disease ... #rheumatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Eosinophilia and Systemic ... extensive skin rash ... Criteria for Diagnosis ... DRESS #Syndrome #dermatology ... #diagnosis #management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Neuropsychiatric systemic ... Erythematosus #Diagnosis
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... maculopapular rash ... episode (30%) Systemic ... #AOSD #rheumatology ... #diagnosis #management
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
50,000 patients • Avg ... hemolytic anemia) • Systemic ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... sudden onset of a rash ... - Rash: multiple ... , breast CA - Hematologic ... #dermatology #oncology