11 results
Systemic Lupus Erythematosus (SLE) - Typical Signs/Symptoms
Alopecia, Fever, Malar rash, Photosensitivity, Adenopathies, Lupus pneumonia, Pleurisy, Pancreatitis,
Systemic Lupus Erythematosus ... Typical Signs/Symptoms ... , Fever, Malar rash ... , Oral ulcers, Rash ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features of Systemic ... Photosensitivity, Butterfly rash ... #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... 69% - Malar rash ... #Lupus #Erythematosus ... autoantibodies #signs #symptoms ... #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... lupus erythematosus ... lupus erythematosus ... ANA #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
everywhere) 2) A rash ... the face (many differential ... diagnosis #sle #clues #system ... #erythematosus ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... NPSLE rare, Malar rash ... months to years) Systemic ... Lupus Erythematosus ... comparison #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... mucositis - Rash ... lupus erythematosus ... Symptoms (Sx) in ... #diagnosis #rheumatology
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
Summarized Erythema ab ... (cutaneous or systemic ... presenting with erythematous ... multiforme • Acute systemic ... comparison #table #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Symptoms (SX) in ... ischemia • Skin: Erythematous ... , mucositis • Rash ... • Progressive symptoms ... #Diagnosis #Rheumatology