8 results
diagnosis hematology neurology rheumatology activation apml differentiation dress encephalopathy gravis hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis macrophage mas myasthenia oncology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ab to AChR blocks ... dystrophy - Brain stem ... /Edrophonium test ... Labs: - AchR antibodies ... Gravis #diagnosis #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
Symptoms (DRESS) Syndrome ... Treatment Stop ... LFTs daily • Cr ... #Treatment #Management ... #dermatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... 5 or elevated Cr ... Prednisone 5mg/kg ... APML #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Infection (eg ... Liver function tests ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
bone marrow or stem ... circulation: MCA ACA ... epilepticus Treatment ... underlying cause • Treatment ... #diagnosis #management
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... blockers had the best ... Rheumatology #diagnosis #management ... #Dermatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Treatment Approach ... Hematopoietic stem ... #Hematology #HemeOnc
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