21 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
of Glomerular Diseases ... • Breaks in GBM ... #Glomerular #Diseases ... #differential # ... spectrum #diagnosis #nephrology
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
Algorithm and Differential ... intrinsic renal disease ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria ... #Macroscopic #Differential
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... , liver, renal disease ... history #Diagnosis #EM ... #IM #Nephro #Hyponatremia ... Pseudohyponatremia #Differential
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Injury (AKI) - Differential ... Immune-complex disease ... , Anti-GBM • Tubular ... Bilateral ureteral disease ... #Diagnosis #nephrology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Syphilis, Lyme disease ... Charcot-Marie-Tooth, Fabry's disease ... Willis via UNC IM ... Peripheral #Neuropathy #differential ... diagnosis #causes #neurology
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Origin (FUO) - Differential ... Neoplasm: • NHL ... fever • Lyme disease ... • Whipple's disease ... Infection: • HIV • EBV
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
and interstitial disease ... GBM, Glomerular ... Kidney #Injury #Differential ... Causes #Sites #Nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Classification #Differential ... #Diagnosis #Nephrology
CNS Ring-Enhancing Lesions - Immunocompromised vs Immunocompetent
Multiple Ring-Enhancing Lesions:
 • Toxoplasmosis (CD4 < 100)
 • Other
granulomatosis: • EBV-associated ... lymphoproliferative disease ... • Metastatic disease ... Lesions #Brain #differential ... causes #radiology #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Goodpasture's Disease ... anti-ANCA ab, anti-GBM ... Renal #Syndrome #differential ... #diagnosis #nephrology