8 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... Proteinuria often ... #Glomerular #Diseases ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Algorithm Persistent Proteinuria ... proliferative • Anti-GBM ... Minimal change disease ... #Nephrology #Differential
Algorithm and Differential Diagnosis of Macroscopic Hematuria
Important Historical Elements:
- Painless: suggests malignancy
- Painful: suggests calculi/infection
- Urinalysis:
RBC/WBC casts, proteinuria ... intrinsic renal disease ... prostatic) #Diagnosis #EM ... #IM #Urology #Hematuria
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
of glomerular disease ... (hematuria, proteinuria ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Differential #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
overt glomerular proteinuria ... Cytomegalovirus; GBM ... impairment), heart disease ... diagnosis cluster, the diseases ... nephrotic #syndrome #nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
vasculitis, Behcet disease ... Goodpasture's Disease ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
RBC casts, +/- proteinuria ... (Dense deposit disease ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
selected glomerular diseases ... Immunofluorescence Microscopy (IM ... Electron Microscopy (EM ... RPGN • Anti-GBM ... #nephrology #pathology