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diagnosis differential acute aki proteinuria classification comparison diseases hematuria injury kidney nephritic renal workup blood glomerulonephritis hyponatremia kidneyinjury low membranoproliferative
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Syndrome Step ... /nephritic syndromes ... the patient have glomerular ... hematuria (RBC casts ... #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome—due ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... Immunofluorescence Microscopy (IM ... Nephrotic syndrome ... polyangiitis #glomerular ... #diseases #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular ... #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... presenting with overt glomerular ... = glomerular basement ... #diagnosis #glomerular ... #syndrome #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... → Refer to Nephrology ... if cause not identified ... by UW IM Residency
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Fanconi's syndrome ... • Drugs Glomerular ... #Proteinuria #Nephrology
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
a.k.a. cardiorenal syndrome ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... Acute interstitial nephritis ... Classification #diagnosis #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal Syndrome ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
dysmorphic RBC, RBC casts ... formation along glomerular ... anti-phospholipid syndrome ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
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