25 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... Proteinuria often ... Massive proteinuria ... #Nephrology #Diagnosis
Glomerular Diseases - Spectrum
 - Insidious vs Acute
 - Nephritic (hypertension, hematuria, renal failure) vs Nephrotic
Glomerular Diseases ... Nephrotic (Heavy proteinuria ... Mehr @poyanmehr #Glomerular ... #differential #diagnosis ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Nephrology #Differential ... #Diagnosis #Algorithm
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... • Evidence of glomerular ... bleeding (proteinuria ... → Refer to Nephrology ... identified by UW IM
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... disease (hematuria, proteinuria ... post-infectious GN Anti-Glomerular ... #Differential #Diagnosis ... #Nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... Comparison #Algorithm #Nephrology ... #Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... #differential #diagnosis ... #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
proteinuria. ... Cytomegalovirus; GBM ... Overglomerular proteinuria ... #glomerular #proteinuria ... nephrotic #syndrome #nephrology
Kidney Biopsy - Diagnosis Algorithms
1) Normal Glomerulus by LM
2) Glomerular Crescents
3) Double Contours of GBM
4) Endocapillary
Kidney Biopsy - Diagnosis ... Glomerulus by LM 2) Glomerular ... Double Contours of GBM ... Biopsy #renal #Diagnosis ... #Algorithm #nephrology
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... • Breaks in GBM ... formation #Glomerular ... differential #spectrum #diagnosis ... #nephrology #nephritic