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diagnosis differential algorithm hematuria proteinuria blood membranoproliferative nephrotic renal urology acute aki atlas casts classification diseases electronmicroscopy gbm glomerulonephritis key
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
kidney injury (AKI ... vascular supply; glomerular ... GBM, Glomerular ... Acute #Kidney #Injury ... #Sites #Nephrology
This image shows acellular scanning EM showing glomerular basement membrane duplication at high power in a
showing glomerular ... high power in a glomerulus ... membranoproliferative #injury ... ElectronMicroscopy #SEM #clinical ... #nephrology #pathology
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 Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... blood cells on urine ... • Calculi Glomerular ... epithelial side of glomerular ... endothelial side of glomerular
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Acute tubular injury ... red - cells Non-glomerular ... Dysmorphic red cells - Glomerular ... Diagnostic of glomerular ... key #diagnosis #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... Immune mediated injury ... of Glomerular Bleeding ... hematuria • Signs of glomerular ... Suggestive of glomerular
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... RBC casts in urine ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified ... by UW IM Residency
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... proliferative • Anti-GBM ... #Proteinuria #Nephrology ... Diagnosis #Algorithm #Causes
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
presenting with overt glomerular ... Cytomegalovirus; GBM ... = glomerular basement ... differential #diagnosis #glomerular ... nephrotic #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... immune deposits on EM ... Glomerulonephritis #MPGN #nephrology
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