13 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... • Breaks in GBM ... formation #Glomerular ... spectrum #diagnosis #nephrology ... #nephritic #nephrotic
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... - Nephritic and ... to GBM disruption ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
Immunofluorescence Microscopy (IM ... ) Haematuria/nephritis ... Haemolytic-uraemic syndrome Nephrotic ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
with evidence of glomerular ... nephropathy, lupus nephritis ... post-infectious GN Anti-Glomerular ... + • c-ANCA: anti-proteinase ... Differential #Diagnosis #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
• Calculi Glomerular ... nephropathy • Thin GBM ... • Hereditary nephritis ... wall) • Anti-GBM ... and >3.5g/day (nephrotic
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... @PulmPEEPs #Anti ... AntiGBM #diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
• Vascular • Glomerular ... Immune-complex disease, Anti-GBM ... Differential #Diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
formation along glomerular ... immune deposits on EM ... microangiopathy (TMA), anti-phospholipid ... glomerulopathy, radiation nephritis ... Glomerulonephritis #MPGN #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... = glomerular basement ... clusters because nephritic ... #proteinuria #nephrotic ... #syndrome #nephrology