13 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... polyangiitis, Microscopic ... ab, anti-GBM ab ... #differential # ... diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework

PRE-Renal AKI:
 • Hypovolemia
 • Congestion
 • Medications
 •
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework PRE-Renal ... , Anti-GBM • Tubular ... #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Diagnosis Framework Pre-Renal ... Vasculitis • GN: ANCA, Anti-GBM ... #Diagnosis #nephrology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
classified into pre-renal ... and interstitial disease ... GBM, Glomerular ... #Injury #Differential ... Causes #Sites #Nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... • Lupus ISN/RPS ... Amyloid RPGN • Anti-GBM ... #nephrology #pathology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... diseases with pulmonary ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... #Pulmonary #Renal
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... dipstick, urine microscopy ... Vasculits: ANCA, ANA, Anti-GBM ... , Anti-ds-DNA, C3 ... #Diagnosis #nephrology
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Henoch-SchonIein Purpura Anti-GBM ... • Limited to Kidney ... : Anti-GBM Glomerulonephritis ... involvement: Anti-GBM ... Disease (Goodpasture's
Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
Guide to Acute Kidney ... - Urinalysis/microscopy ... ATN - 45% - Pre-renal ... disease — 21% ... mostly ATN and pre-renal
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute Kidney ... at least 50% Renal ... Glomerulonephritis • Anti-GBM ... polyangiitis /microscopic ... #KidneyInjury #Nephrology