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diagnosis differential pulmonary vasculitis acute algorithm anca antibodies antibody antineutrophil antinuclear classification glomerulonephritis injury kidney management membranoproliferative mpgn prs syndrome
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... , ANA, Anti-GBM, ... Anti-ds-DNA, C3 ... Differential #Diagnosis #nephrology ... #causes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Vasculitis: • Microscopic ... polyangiitis without renal ... + 30-60% • Renal-limited ... + 90% • Anti-GBM ... antibodies #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... testing: anti-ANCA ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
: (AKI, proteinuria ... antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause ... diagnosis #management #treatment
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Glomerulonephritis (MPGN) AKA ... (Dense deposit disease ... microangiopathy (TMA), anti-phospholipid ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
renal abnormalities ... often causes arthritis ... glomerulonephritis) • Anti-GBM ... LFT • ESR • ANA ... differential #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
renal abnormalities ... )): Microscopic ... often causes arthritis ... GN Anti-GBM (10 ... Differential #Diagnosis #Rheumatology
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