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differential algorithm renal causes hematuria proteinuria blood nephrotic pulmonary syndrome syndromes urology atlas classification comparison glomerulonephritis interpretation key management membranoproliferative
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
Atlas of Urine Microscopy ... tubular cells - Acute ... - Diagnostic of ... glomerular disease ... #nephrology #casts
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... (IM) - Electron ... Microscopy (EM) ... #diseases #nephrology ... comparison #table #diagnosis
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... #Urine #Microscopy ... #nephrology #interpretation ... #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... syndrome—due to GBM ... RBC casts in urine ... #Proteinuria #Nephrology ... #Diagnosis
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup and Diagnosis ... repeat testing • Acute ... • Evidence of glomerular ... proteinuria, RBC casts ... identified by UW IM
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... hematuria: - RBC casts ... disease Renal ... causes #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts ... disease •
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... are seen in acute ... #Differential #Microscopy ... #Diagnosis #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... arbitrarily defined as urine ... cell/white cell casts ... cluster, the diseases ... nephrotic #syndrome #nephrology
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