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differential causes pulmonary renal acute aki algorithm hematuria kidney antigbm blood classification comparison disease glomerular glomerulonephritis goodpastures locations management membrane
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #GIomeruIar #Basement ... #nephrology #pulmonary
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology ... comparison #table #diagnosis
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
and interstitial disease ... GBM, Glomerular ... basement membrane ... #Diagnosis #AKI ... Causes #Sites #Nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... Basement Membrane ... ab, anti-GBM ab ... #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
disease (hematuria ... post-infectious GN Anti-Glomerular ... Basement Membrane ... #Differential #Diagnosis ... #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... disease • ... wall) • Anti-GBM ... • Pauci-immune disease
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
Acute Kidney Injury ... - Differential Diagnosis ... • Vascular • Glomerular ... , Anti-GBM • Tubular ... #nephrology
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
Immune mediated injury ... nephropathy - Thin basement ... membrane disease ... disease Renal ... causes #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... quantify renal injury ... ANCA antibody, Anti-GBM ... usually low in anti-GBM
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