14 results
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... polyangiitis, Microscopic ... anti-ANCA ab, anti-GBM ... #differential # ... diagnosis #nephrology
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Haemolytic-uraemic syndrome ... Nephrotic syndrome ... glomerular #diseases #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Injury (AKI) - Differential ... Abdominal Compartment Syndrome ... Emboli, Thrombosis, Vasculitis ... GN: ANCA, Anti-GBM ... #Diagnosis #nephrology
Etiologies of Peripheral Neuropathy
 • Metabolic / Nutritional: DiabetesB12 deficiency, Uremia/ESRD, Hypothyroidism
 • Medication-induced: ART, Antibiotics,
Guillain-Barre, Vasculitis ... Paraprotein-associated (POEMS syndrome ... Willis via UNC IM ... Peripheral #Neuropathy #differential ... diagnosis #causes #neurology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential ... PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... • Cogan Syndrome ... Dx: GPA, EGPA, microscopic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
dipstick, urine microscopy ... Glomerulonephritis / Vasculits ... ANCA, ANA, Anti-GBM ... • Cardio-renal syndrome ... #Diagnosis #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
Hematuria - Differential ... pain hematuria syndrome ... Diagnostic of GN or vasculitis ... #Hematuria #Differential ... causes #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Proteinuria - Differential ... • Fanconi's syndrome ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology ... #Differential #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Weakness - Differential ... • Acute stroke syndromes ... Coxsackie, HIV, CMV, EBV ... #Weakness #Differential ... #Diagnosis #neurology
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... polyangiitis), MPA (microscopic ... palpable purpura 2/2 vasculitis ... FINDINGS: • U/A: microscopic ... #differential #