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diagnosis differential pulmonary rheumatology diseases renal vasculitis acute aki algorithm ana anca antibodies antibody antineutrophil antinuclear classification comparison giomeruiar glomerular
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... • Lupus ISN/RPS ... Amyloid RPGN • Anti-GBM ... #nephrology #pathology
Causes of acute kidney injury (AKI). AKI is classified into pre-renal, renal, and post-renal causes. Renal
classified into pre-renal ... and interstitial disease ... GBM, Glomerular ... basement membrane ... #Sites #Nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... #Goodpastures #AntiGBM ... #diagnosis #nephrology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... Basement Membrane ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
of cases) 2 ... connective tissue disease ... Vasculitis: • Microscopic ... ANCA+ 90% • Anti-GBM ... disease - MPO>PR3
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... Goodpasture's cause
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
-ANCA): • Microscopic ... tract, and often causes ... glomerulonephritis) • Anti-GBM ... Urticarial Vasculitis (anti-C1q ... Dx: GPA, EGPA, microscopic
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
-ANCA)): Microscopic ... tract, and often causes ... abdominal pain and GN Anti-GBM ... Urticarial Vasculitis (anti-C1q ... Urticarial Vasculitis (anti-C1q
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