11 results
diagnosis differential pulmonary algorithm causes classification renal rheumatology vasculitis acute aki antigbm basement disease giomeruiar glomerulonephritis goodpastures hematuria injury kidney
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Amyloid RPGN • Anti-GBM ... #diseases #nephrology ... #pathology #comparison
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
disease (hematuria ... post-infectious GN Anti-Glomerular ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... Differential #Diagnosis #Nephrology
Spectrum of Glomerular Diseases Nephrotic - Mechanism: • Injury to podocytes • Changed architecture: Scanning. Deposition of
Spectrum of Glomerular ... Diseases Nephrotic ... • Breaks in GBM ... spectrum #diagnosis #nephrology ... nephritic #nephrotic #comparison
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... ab, anti-GBM ab ... biopsy By Tess Litchman ... differential #diagnosis #nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... nephropathy • Thin GBM ... disease • ... wall) • Anti-GBM ... • Pauci-immune disease
Acute Kidney Injury (AKI) - Differential Diagnosis Framework PRE-Renal AKI: • Hypovolemia • Congestion • Medications •
• Vascular • Glomerular ... Immune-complex disease ... , Anti-GBM • Tubular ... Bilateral ureteral disease ... Differential #Diagnosis #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
Anti-GIomeruIar ... directed against the glomerular ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... AntiGBM #diagnosis #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... ANCA antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... Vasculitis - Skin, glomeruli ... : - Kidneys: glomerular ... Dx: GPA, EGPA, microscopic
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