9 results
Spectrum of Glomerular Diseases
Nephrotic - Mechanism:
 • Injury to podocytes
 • Changed architecture: Scanning. Deposition of
Diseases Nephrotic ... • Breaks in GBM ... #spectrum #diagnosis ... #nephrology #nephritic ... #nephrotic #comparison
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... RPGN • Anti-GBM ... #diseases #nephrology ... #table #diagnosis
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... #Diseases #Nephritic ... #Proteinuria #Nephrology ... #Diagnosis
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... cells on urine microscopy ... nephropathy • Thin GBM ... disease • ... ) • Anti-GBM
Rapidly Progressive Glomerulonephritis (RPGN) 
 - Loss of kidney function over a short period of tirne
disease (hematuria ... nephropathy, lupus nephritis ... Basement Membrane (GBM ... Linear, ribbon-like GBM ... #Nephrology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... anti-ANCA ab, anti-GBM ... #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... impairment), heart disease ... cluster, the diseases ... #nephrotic #syndrome ... #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease)

What is it? A small vessel vasculitis with circulating antibodies directed
directed against the glomerular ... hemorrhage Diagnosis ... : • Anti-GBM antibodies ... weeks By Tess Litchman ... #nephrology #pulmonary