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diagnosis differential pulmonary algorithm glomerulonephritis pathology proteinuria renal syndrome anti causes classification clinical comparison disease electronmicroscopy giomeruiar glomerulus goodpastures management
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... (IM) - Electron ... Microscopy (EM) ... RPGN • Anti-GBM ... #diseases #nephrology
Anti-GIomeruIar Basement Membrane Disease (Goodpasture's Disease) What is it? A small vessel vasculitis with circulating antibodies directed
directed against the glomerular ... Diagnosis: • Anti-GBM ... weeks By Tess Litchman ... #AntiGBM #diagnosis ... #nephrology #pulmonary
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
disease (hematuria ... Basement Membrane ... (GBM) • Typically ... Linear, ribbon-like GBM ... Differential #Diagnosis #Nephrology
Stage IV Glomerulonephritis on Electron Microscopy This image shows acellular scanning EM of glomerular capillary loops from
Glomerulonephritis on Electron Microscopy ... second layer of basement ... completely bridged GBM ... #MGN #stage4 #ElectronMicroscopy ... SEM #clinical #nephrology
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 Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... Basement Membrane ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... = glomerular basement ... impairment), heart disease ... diagnosis cluster, the diseases ... nephrotic #syndrome #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Proteinuria #Nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
polyangiitis) Anti-basement ... life-threatening diseases ... antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli
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