11 results
diagnosis differential algorithm classification renal causes glomerulonephritis pulmonary rheumatology syndrome syndromes vasculitis comparison hematuria management membranoproliferative mpgn nephritic pathology prs
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... to GBM disruption ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Nephrology #Diagnosis
Summary of characteristic abnormalities of selected glomerular diseases Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
(IM) - Electron ... Microscopy (EM) ... Haematuria/nephritis ... RPGN • Anti-GBM ... #diseases #nephrology
Rapidly Progressive Glomerulonephritis (RPGN) - Loss of kidney function over a short period of tirne
disease (hematuria ... , proteinuria) ... nephropathy, lupus nephritis ... Basement Membrane (GBM ... Linear, ribbon-like GBM
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
cells on urine microscopy ... nephropathy • Thin GBM ... disease • ... ) • Anti-GBM ... range) proteinuria
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Drugs Glomerular ... proliferative • Anti-GBM ... polyangiitis (GPA) / microscopic ... Minimal change disease ... #Nephrology #Differential
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Cytomegalovirus; GBM ... impairment), heart disease ... clusters because nephritic ... #proteinuria #nephrotic ... #syndrome #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
RBC casts, +/- proteinuria ... formation along glomerular ... (Dense deposit disease ... glomerulopathy, radiation nephritis ... #nephrology #diagnosis
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
polyangiitis, Microscopic ... sclerosis • Anti-Glomerular ... • Urinalysis (proteinuria ... anti-ANCA ab, anti-GBM ... differential #diagnosis #nephrology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... antibody, Anti-GBM ... usually low in anti-GBM ... hypercellular glomeruli ... in crescentic GN
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Hematuria, proteinuria ... rapidly progressing GN ... PR3-ANCA): • Microscopic ... glomerulonephritis) • Anti-GBM ... : - Kidneys: glomerular
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