36 results
Lens Retrodots and Vacuoles - Slit Lamp Ocular Examination

Vacuoles in posterior subcapsular cataract - lens retrodots
Retrodots and Vacuoles ... Examination Vacuoles ... retrodots and vacuoles ... #Retrodots #Vacuoles
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
VEXAS (Vacuoles, ... VEXAS #Syndrome #Vacuoles
Central Distribution, Febrile / Ill:
 - Viral Exanthem 
 - Lyme Disease (erythema migrans) 
Central Distribution,
Maculopapular #Macular #Macules
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Host disease: vacuolar
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
inclusions, rimmed vacuoles
Hansen's Disease (Leprosy)
 • Transmission - not completely understood, ?nasal droplets
 • Symptoms appear ~5 years
Macrophages with a vacuolar
Bilateral Foot Drop secondary to Nonaka Myopathy

48 yr old lady, difficulty in climbing stairs x 8
myopathy with rimmed vacuoles
Hydroxychloroquine - Risks and Benefits in Lupus
Benefits:
↓ Disease activity, ↓ Flare, ↓ Damage, ↓ Corticosteroid dose,
Neuro-muscular: vacuolar
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
anhydrase and vacuolar
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm

HYPOPIGMENTATION
Diffuse Congenital - Generalized hypopigmentation of
white "ash leaf" macules ... • Café au lait macules