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diagnosis hepatology causes lactate lfts transaminitis acidosis chemistry children cholestatic classification dehydrogenase dili drug effusion elevated enzymes gastroenterology hepatitis hepatocellular
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Injury ... • AST/ALT elevation ... • R value = (ALT ... Transaminitis #diagnosis #differential ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... Calculate R-Value ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... #differential # ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Bilirubin - +/- elevation ... Enzyme Elevation ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Causes of Pleural Effusion - Differential Diagnosis Algorithm Transudate - Hydrostatic • Congestive heart failure • Constrictive
Pleural Effusion - Differential ... Diagnosis Algorithm ... • Subphrenic abscess ... • Postcardiac injury ... #Hepatology #causes
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Pyogenic liver abscess ... ) • Traumatic injury ... #children #peds ... #differential # ... diagnosis #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... to bolus these values ... or renal injury ... output - Acute pulmonary ... #Differential #
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... RBCs, muscle, liver ... - Prosthetic valves ... Legionnaires disease • Pulmonary ... Idiosyncratic LDH Elevation
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... Hematologic malignancy ... gastrointestinal symptoms (elevations ... of liver enzymes ... NTM #Infections #differential
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