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Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Generalized Weakness - Differential ... feel weak": • Infectious ... Resp/Heme: CHF, valves ... ↓, Malignancy, Infection ... Generalized #Weakness #Differential
Faget's Sign & Liebermeister's Rule Pulse-Temperature Dissociation EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM INFECTIOUS
INCREASES 8-10 BPM INFECTIOUS ... limited predictive value ... the most likely infection ... help hone your differential ... Dissociation #diagnosis #differential
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Internal (RBC) - Infections ... #Hemolysis #Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis - Differential ... circulation - Infections ... Prosthetic heart valves ... Extravascular #Differential
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Inflammatory disease • Infection ... Urethral stricture/valves ... Postrenal #Failure #Differential
Right-Sided Heart Failure - Differential Diagnosis Algorithm Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Heart Failure - Differential ... Cardiomyopathy - Valves ... • Chronic Lung Infection ... HeartFailure #Cardiology #Differential
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Neutrophil (Normal) Differential ... appreciate the value ... overlook severe infections ... superior indicator of infection ... #Bandemia #differential
Non-Infective Endocarditis (NBTE / Marantic Endocarditis) Non-infective endocarditis is also known as: Non-bacterial thrombotic endocarditis (NBTE), Aseptic
left-sided heart valves ... embolize • Cannot differentiate ... absent How can we differentiate ... - Infectious Diseases
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... - Prosthetic valves ... • Toxins • Infection ... Dehydrogenase #Elevated #differential
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
or sed rate): Value ... very remarkable w/differential ... vasculitis vs infection ... GCA, but normal values
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