23 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... or higher • Liver ... bile ducts Differential ... #workup #hepatology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Thrombosis - Differential ... Diagnosis Framework ... Syndrome, Ischemic Liver ... #pathophysiology ... #hematology #differential
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... thin smear • Signs ... biopsy • Lab values ... supporting hematologic ... #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... bypass), LFT (liver ... #Workup #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... #Diagnosis #hematology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... #Dermatology #Rash ... Targetoid #Algorithm #Differential ... #Ddxof
Age-Focused Initial Evaluation for Pyoderma Gangrenosum 

All Patients: 
 - A thorough history and physical examination
tissue culture (bacterial ... mycobacterial) - CBC ... with differential ... #Gangrenosum #Workup ... #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... signs of end organ ... Syndrome #TLS #diagnosis ... #management #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... pericarditis • Hepatic: PBC ... PAH (pulmonary arterial ... #diagnosis #signs ... symptoms #testing #workup
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... • LDH: Heart, RBC ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis