7 results
diagnosis differential chemistry interpretation laboratory tests algorithm alkphos astalt biliary cholangitis cirrhosis dili drug function hemolysis idiosyncratic induced injury management
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Cholangitis #pathophysiology ... #pbc #psc #hepatology ... #comparison
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... Values and Interpretation ... Function #Tests #LFTs ... #Laboratory #Values ... Interpretation #diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Liver Chemistry ... Phosphatase and Bilirubin ... initial insult Bilirubin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... week • Direct bilirubin ... #differential #Hepatology ... transaminitis #LFTs
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... 2) External (RBC ... Defects, Drugs, Liver ... - Unconjugated Bilirubin ... Differential #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... cholestasis → Cirrhosis/Liver ... slightly elevated • Bilirubin ... or higher • Liver ... diagnosis #workup #hepatology
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