13 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Calculate R-Value ... #gastroenterology ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... ) - Normal Values ... Function #Tests #LFTs ... #Laboratory #Values ... Interpretation #diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... EmoryGastroHep #ACLF #Acute ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Chemistry #Tests #Laboratory ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... - ACS, AKI, acute ... priapism • Lab values ... TLS #diagnosis #management ... #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... Pregnancy (AFLP) Pathophysiology ... headache, malaise) → Acute ... Liver #Pregnancy #hepatology ... #pathophysiology
Fontan-Associated Liver Disease

By Dr. Andrew Yu @michaelandrewyu via @EmoryGastroHep

#FALD #Fontan #Associated #Liver #Disease #gastroenterology #hepatology #pathophysiology
Liver #Disease #gastroenterology ... #hepatology #pathophysiology ... #diagnosis #management
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... R-value: Serum ... Mixed - Check Acute ... #differential #Hepatology ... transaminitis #LFTs
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Sweet Syndrome (Acute ... Abnormal laboratory ... values at presentation ... Sweet #Syndrome #Acute ... Criteria #Diagnosis #Hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... Hepatitis (eg Viral) Management ... Necrosis) If mild laboratory ... AIH #Diagnosis #Management ... #Hepatology