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Sickle Cell Disease - Pathophysiology of disease and complications Due to the deformed shape, HbS induces
- Pathophysiology ... complications ... #Pathophysiology ... #Complications ... #Hematology #Sequelae
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Scleritis, Heart Disease ... Nodules, Pulmonary Disease ... and ILD Complications ... RA #diagnosis #rheumatology ... #signs #symptoms
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... complex storage diseases ... connections and pathophysiology ... See the lab values ... Diagnosis #Algorithm #Differential
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Most common symptoms ... - Bone symptoms ... ALP #Elevation #Differential ... Diagnosis #Algorithm #hepatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- B symptoms ... involvement Differential ... Lymphomas • Other hematologic ... oncology #diagnosis #differential ... #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... autoinflammatory diseases ... , Schnitzler) Complications ... management #treatment #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... , Drugs, Liver Disease ... #Hemolysis #Differential ... #Diagnosis #hematology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Monitor and Treat Complications ... Liver #Pregnancy #hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... Lysis Syndrome: • Pathophysiology ... sudden death • Lab values ... diagnosis #management #hematology
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