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diagnosis hepatology signs algorithm management alkaline alp causes gastroenterology phosphatase psychiatry transaminitis workup abnormal aflp anorexianervosa arterial arteritis bariatric biliary
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Complications of Measles: Pathogenesis and Clinical Findings • ADEM -> Fever, headache, neck stiffness, BBD, mental
Complications of ... N/V, elevated liver ... enzymes • Immunosuppression ... diagnosis #signs #symptoms ... #pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... Enzymes - Budd ... Gastrointestinal #Complications ... #pathophysiology ... #signs #symptoms
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... or symptoms of ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... • Others #LFTs ... #Hepatology #LiverEnzymes ... #Differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... Monitor and Treat Complications ... #Pregnancy #hepatology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... the magnitude of enzyme ... #LFTs #Abnormal ... #Liver #Enzymes ... #Differential #
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Algorithm ALP: - Enzymes ... disturbance (obstructed liver ... Highest • Bone • Liver ... Most common symptoms
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... R-value: Serum ... Enzyme Elevation ... chemistry #diagnosis #differential ... #LFTs #RValue #
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Defects, Drugs, Liver ... , Spiders - Enzyme ... #Diagnosis #hematology
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