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differential hepatology management rheumatology workup algorithm primary syndrome alkaline arthritis autoimmune biliary causes cholangitis cirrhosis lfts phosphatase abnormal aih als
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
- Differential Diagnosis ... Highest • Bone • Liver ... Most common symptoms ... - Bone symptoms ... #Algorithm #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Algorithm Symptoms ... quadrant discomfort Signs ... Elevated ALP 2. ... Liver biopsy findings ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... Signs and Symptoms ... obstruction • ALP ... or higher • Liver ... #workup #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... of cholestatic disease ... disease: > 2 ... #chemistry #diagnosis ... #differential #Hepatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... signs of end organ ... Syndrome #TLS #diagnosis ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... pylori test (GI symptoms ... (CVID, WAS), (neurologic ... disease), HBsAg ... not required in all
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
Chondrodysplasia Neurologic ... Trendelenburg #Gait #pathophysiology ... #causes #symptoms ... #signs #diagnosis ... #msk
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
suspicious clinical symptoms ... /signs should be ... ALP, alkaline phosphatase ... body mass index; FBC ... disease; T2DM,
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Workup • CNS symptoms ... thin smear • Signs ... biopsy • Lab values ... supporting hematologic ... UnknownOrigin #workup #diagnosis
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... indications for liver ... Care focuses on symptom ... #Cholangitis #diagnosis ... management #summary #Hepatology
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