57 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... : INR/PT, aPTT(liver ... pylori test (GI symptoms ... bypass), LFT (liver ... #Differential #
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Bleeding / Bruising - Differential ... Sequestration Disordered ... Connective Tissue Disorders ... Iatrogenic) • Liver ... Algorithm #Causes #Hematology
Approach to a Positive (+) Rheumatoid Factor (RF)
(+) RF does not always = RA
Rheumatic disorders:
 •
RA Rheumatic disorders ... • Inflammatory disorders ... of Liver & Lung ... Rheumatoid #Factor #RF #rheumatology ... #laboratory #differential
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Pancreatitis - Elevated Liver ... Esophageal Motility Disorders ... Complications #pathophysiology ... #signs #symptoms
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
ongoing ↑ LFTs or symptoms ... of liver disease ... Calculate R-Value ... Idiosyncratic #differential ... gastroenterology #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... • R value = (ALT ... Transaminitis #diagnosis #differential ... #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... postpartum): • Initial symptoms ... infiltration) Differential ... #Pregnancy #hepatology ... diagnosis #management #pathophysiology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... deficiency • Liver ... Vasculopathy #Purpura #Differential ... #Diagnosis #hematology ... #rheumatology #
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
Non-hemolytic Disorders ... of hemolysis or liver ... examination; nonspecific symptoms ... • Disorder is ... Congenital #bilirubin #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Volume (MCV) - Differential ... • Small Bowel Disorder ... Tests • Liver ... #elevatedMCV #Differential ... Algorithm #Causes #Hematology