9 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
of Tumor Lysis Syndrome ... : • Uric acid ... 8.0 mg/dL • Potassium ... #TumorLysis #Syndrome ... #management #oncology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Losses: • Normal Acid-Base ... #causes #potassium ... #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... starts by measuring ... , glycyrrhizic acid ... #causes #nephrology ... #potassium
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... , glycyrrhizic acid ... #nephrology #causes ... #low #potassium
Hypokalemia Diagnostic Algorithm
To assess potassium excretion: perform 24-hour urine collection or alternatively obtain potassium-to-creatinine ratio on
Algorithm To assess ... ratio on a spot ... be <3; greater values ... #Algorithm #TTKG ... #nephrology #low
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
priapism • Lab values ... Elevated uric acid ... hydration - Hyperkalemia ... #TLS #diagnosis ... #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... HIV, Influenza, TSS ... Monitor potassium ... Differential #Diagnosis #Management ... causes #treatment #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
(renal potassium ... Hypocalciuria (spot ... Supplement: • Potassium ... #diagnosis #nephrology ... #management #pathophysiology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
mobilizes fatty acids ... for Refeeding Syndrome ... provided the starting potassium ... #differential #algorithm ... #management #treatment