11 results
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... • Euvolemic (Low ... Hypervolemic: Conn syndrome ... , Cushing syndrome ... #Algorithm #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Based Approach to Hyponatremia ... Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... diagnosis #sodium #low ... #nephrology
NSAIDS and their effects on the Kidney - Pathophysiology

Arachidonic Acid metabolites into alternative pathways that modify
on the Kidney - Pathophysiology ... Arachidonic Acid ... distal nephron: Hyponatremia ... decreased renal blood flow ... KidneyDisease #nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... : • Pathophysiology ... Elevated uric acid ... , Elevated Cr, Low
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... occurs due to a low ... Pinpoint-sized red spots ... vitamin B12 or folic acid ... Workup: • Complete
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Guillain-Barre Pathophysiology ... • Weakness: Starts ... /constipation, hyponatremia ... management #treatment #neurology
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... And BMP Normal Values ... D D-lactate (short ... bowel syndrome, ... ABG #bloodgas #Acid
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
and ulcers • Vagus ... • Boerhaave syndrome ... hormonal imbalances (low ... hypochloremia, hypernatremia ... Complications #pathophysiology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
mobilizes fatty acids ... produce Acetoacetic acid ... hormones that work ... for Refeeding Syndrome ... both conditions, low
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... Phos, high uric acid ... , high LDH, low ... high d-dimer, low