8 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... - Differential Diagnosis ... Chronic Viral Hepatitis ... Drug-induced liver injury ... #hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
→ liver test abnormalities ... • Infections: Hepatitis ... #hepatology #algorithm ... #Transaminitis ... #LFTs #hepatitis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... ALP ≥ 2x ULN R Value ... Hepatocellular injury ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... liver #chemistry #diagnosis ... #differential #Hepatology ... #transaminitis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... atypical laboratory tests ... #diagnosis #Alcoholic ... #hepatology #criteria
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... >1.5, and both values ... atypical laboratory tests ... #Diagnosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... extrahepatic source - Tests ... Chronic viral hepatitis ... #diagnosis #algorithm ... #hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
to bolus these values ... presentations and disease ... liver or renal injury ... / hypoxemia -> focus ... tests before beginning