15 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Laboratory Tests ... Blood Smear ↑ abnormal ... #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... hallmark for the disease ... If the value is ... low, tests to detect ... #Workup #Hematology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... upon damage • Normal ... - Prosthetic valves ... • Legionnaires disease ... #differential #diagnosis
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Saturation 90%, Abnormal ... Abdominal Ultrasound ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... >1.5, and both values ... atypical laboratory tests ... #diagnosis #Alcoholic ... #hepatology #criteria
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... extrahepatic source - Tests ... function may be abnormal ... #differential #diagnosis ... #algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... >1.5, and both values ... atypical laboratory tests ... #Diagnosis #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... of cholestatic disease ... Alcoholic liver disease ... liver #chemistry #diagnosis ... #differential #Hepatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... mellitus; USS, ultrasound ... #Algorithm #Hepatology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Liver Disease in ... HELLP Syndrome (Hemolysis ... #Pregnancy #hepatology ... #obstetrics #hepatitis ... #differential #diagnosis