26 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
risk-stratification • Risks: infection ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... Coagulation Failure Infections ... Failure #Cirrhosis #Hepatology ... #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
: • Recurrent infections ... Symptomatic anemia Diagnosis ... progress to MDS or acute ... #management #treatment ... #hematology
Invasive Aspergillus (IA) - Diagnosis and Management
Aspergillus is ubiquitous in nature. Most invasive infections are caused
and Management ... neutropenia (performs best ... septated hyphae, acute ... this morphology Treatment ... #Management #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : Infection (sepsis ... Renal Failure Treatment ... #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... presents as an acute ... : • Infection ... #management #treatment ... #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
skin necrosis (at injection ... approach for post-test ... : Confirmatory test ... #Management #Treatment ... #Hematology #HemeOnc
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
presents with acute ... to 12 weeks for acute ... Pulmonary 3) Abdominal ... Chronic, subacute to acute ... #Management #Infections