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hepatology lfts transaminitis lactate nephrology abscess acidosis acute algorithm chemistry children cholestatic classification dehydrogenase elevated enzymes failure functiontest heat heatstroke
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
) - Causes of Hepatocellular ... Liver Injury ... • AST/ALT elevation ... • R value = (ALT ... #differential #
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... skeletal muscle, kidney ... ALP ≥ 2x ULN R Value ... Transaminitis #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... Vascular Causes ... extrahepatic source - Tests
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs R-value ... Bilirubin - +/- elevation ... Enzyme Elevation ... #chemistry #diagnosis ... #differential #
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( ... Urethral stricture/valves ... /phimosis #Diagnosis ... Postrenal #Failure #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... to bolus these values ... or renal injury ... tests before beginning ... Diagnosis #causes
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework Heat Cramps: • Muscle pain or spasm -
Diagnosis Framework ... involvement: Muscles, Kidneys ... - Headache - Abdominal ... acidosis - CPK elevation ... #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Tachycardia - N/V - Abdominal ... ULN • AST/ALT Elevation ... nephrotoxicity to kidney
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Diagnosis Framework ... RBCs, muscle, liver ... , and kidney • ... - Prosthetic valves ... Idiosyncratic LDH Elevation
Pyogenic liver abscess in children Common bacterial causes in children: • S.aureus • Strep spp • Enteric
Common bacterial causes ... from contiguous focus ... sources within abdominal ... children #peds #differential ... #diagnosis #hepatology
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