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diagnosis differential management dermatology rheumatology anemia hepatology oncology hyperpigmentation skin systemic approach bilirubin cardiology cardiomyopathy chronic clinicopathology congenital cryofibrinogenemia cryoglobulinemia
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... hematological disorders ... #classification ... #rheumatology #
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
: • Type I CN ... encephalopathy • Type ... type II rarely ... and stress may cause ... Congenital #bilirubin #hepatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Disorders of Pigmentations - Hypopigmentation and Hyperpigmentation - Differential Diagnosis Algorithm HYPOPIGMENTATION Diffuse Congenital - Generalized hypopigmentation of
Disorders of Pigmentations ... Differential Diagnosis Algorithm ... McCune Albright syndrome ... #skin #dermatology ... #causes
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... multifactorial mechanisms Hematologic ... #Differential #Causes
Mucous Membrane Disorder - Differential Diagnosis Algorithm Erosions/Ulcers/Blisters - Primary Dermatologic Diseases •
Mucous Membrane Disorder ... Differential Diagnosis Algorithm ... Stevens-Johnson Syndrome ... • Behcet's syndrome ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... • Somatization Disorder ... Chronic Fatigue Syndrome ... #causes
Major neurocognitive disorders (MNCD): Diagnosis and workup 1) Clinical diagnosis Cognitive impairment + loss of autonomy 2)
neurocognitive disorders ... diagnostic workup What type ... Alzheimer - 1st cause ... Aphaso-apraxo-agnosia syndrome ... Differential #Subtypes #Classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... skin that are caused ... Neutropenia • Platelet Disorders ... #diagnosis #hematology
Restrictive Cardiomyopathy - Diagnosis and Causes Clinical: Dyspnea, Exercise Intolerance, ↑ "Right Sided-Symptoms" (ascites, hepatomegaly, ↑↑peripheral edema) Physical
Diagnosis and Causes ... Amyloid, Wild Type ... Hyper-eosinophilc Syndrome ... Sarcomeric Protein Disorders ... differential #cardiology #algorithm
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