12 results
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
Prevention of first variceal ... bleeding, Prevention ... of variceal rebleeding ... hepatology #management #pharmacology ... #indications #dosing
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
Anticoagulants #Medications ... #Pharmacology # ... Pathophysiology #Mechanisms #DOAC ... #Hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
thereby leading ... metabolization leading ... Chemotherapy #Oncology #Hematology ... #Interactions #Table ... #Pharmacology
Topical drug formulations, comparison and considerations

#pharmacology #table #medications #comparison #drugs #treatment #pharmacotherapy #dermatology
considerations #pharmacology ... #table #medications ... pharmacotherapy #dermatology
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Summary table of ... anticoagulation #pharmacology ... #medications #doac ... #comparison #table
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
lead to severe bleeding ... management #algorithm #pharmacology ... #treatment #medications ... #table #pharmacotherapy ... decisionaid #cardiology #hematology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
Management of DOACs ... per treatment table ... and procedural bleeding ... with a very low bleeding ... Management #Treatment #pharmacology
Beta Blockers - Pharmacology Comparison Table
Metoprolol:
 • Receptors: β1
 • Indications: Rate control of a-fib/a-flutter, Suppression
Beta Blockers - Pharmacology ... Comparison Table ... Migraine prophylaxis, Variceal ... Beta #Blockers #Pharmacology ... #Comparison #Table
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Tranexamic Acid - Indications ... and Pharmacology ... Hemoptysis, GI Bleeding ... #Pharmacology # ... hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Anticoagulant Medications ... LMWH, warfarin, DOACs ... Deficiencies #Summary #table ... comparison #diagnosis #hematology