46 results
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... portal HTN: • Ascites ... : • Cardiac causes ... sarcoidosis) • Liver ... metastasis • Fatty liver
Approach to the Hospitalized Patient with Cirrhosis
1) Recognize and Manage Decompensation
 • Ascites
 • Variceal Bleeding
Hospitalized Patient with Cirrhosis ... Decompensation • Ascites ... • Variceal Bleeding ... • Hepatic Encephalopathy ... Portosystemic Shunt • Liver
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
End Stage Liver ... Disease (Cirrhosis ... Complications • Ascites ... Esophageal Varices • Hepatic ... #Cirrhosis #Complications
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... Liver disease ... - Cirrhosis ... - Acute fatty liver ... #Causes #diagnosis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... Hypertension - Hepatic ... : • Cirrhosis ... disease • Acute liver ... Hypertension - Post-Hepatic
Ascites - Differential Diagnosis
Chronic liver disease (cirrhosis or chronic hepatitis) - 80%
Underlying malignancy - 10%
Congestive heart
Ascites - Differential ... Diagnosis Chronic liver ... disease (cirrhosis ... failure - 3-5% Cirrhosis ... Disease, Fulminant Hepatic
Clinical Examination for Liver and Biliary Diseases
1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Examination for Liver ... Flapping tremor (hepatic ... Aspiration of ascitic ... #physicalexam #cirrhosis ... #liver #disease
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... for alternative causes ... disease, Hepatic ... presentation: Hepatic ... disorder (e.g. ascites
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... ) - Causes of Hepatocellular ... Liver Injury ... more specific for hepatic ... Injury?
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... • NAFLD • Cirrhosis ... (Drug-induced liver ... injury) • Ischemic ... ) • Non-hepatic