12 results
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG)
SAAG ≥ 1.1:
 - Ascitic protein
albumin gradient ... protein ≤ 2.5 g/dL: Cirrhosis ... , Massive liver ... #albumin #gradient ... #hepatology #differential
Indications for Albumin for Management of Cirrhosis
 • Large volume paracentesis (>5 liter) - 8g per
Indications for Albumin ... Management of Cirrhosis ... of ascites removed ... • Hepatorenal syndrome ... #treatment #hepatology
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... Clues to non-cirrhotic ... portal HTN: • Ascites ... INR, bilirubin, albumin ... #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis
High albumin gradient (>1.1 g/dl):
 - Cirrhosis	
 - Alcoholic
Serum Ascites Albumin ... >1.1 g/dl): - Cirrhosis ... - Massive liver ... - Acute fatty liver ... without cirrhosis
Causes of Ascites - Differential Diagnosis Algorithm
Portal Hypertension - Prehepatic:
 • Portal vein thrombosis
 • Splenic
Causes of Ascites ... - Hepatic: • Cirrhosis ... disease • Acute liver ... Diagnosis #Algorithm #Hepatology ... #causes
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Causes of Ascites ... - Budd-Chiari syndrome ... Liver disease ... - Cirrhosis ... #Causes #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Kasabach-Merritt syndrome ... deficiency • Liver ... meningitidis - Varicella ... Gardner-Diamond syndrome ... vasculitis - GPA
VIBES Mnemonic - Cirrhosis Management Checklist

V - Volume (Ascites, HRS)
	- Evaluate for Ascites, Edema, Hydrothorax, Hepatorenal
VIBES Mnemonic - Cirrhosis ... Hydrothorax, Hepatorenal Syndrome ... B - Bleeding (Variceal ... octreotide, EGD -> variceal ... #Gastroenterology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Total Protein - Albumin ... concentration minus albumin ... changes (POEMS syndrome ... Sarcoidosis) • Liver ... disease: Cirrhosis
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... disease: cirrhosis ... diuretic-resistant ascites ... - IV albumin ... #Hepatorenal #Syndrome