10 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Excretion Effects ... Diuresis, Na+, ... Thiazide Type - Loop ... electrolytes #effects #pharmacology ... #comparison #table
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Sites of Action ... Diuretics 1) ... urearetics) 3) Loop ... #Sites #Action ... #nephrology #pharmacology
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... . mannitol) 3) Loop ... #pharmacology # ... nephrology #medications ... #sites #action
Pharmacology of diuretics

Acetazolamide, Loop diuretics, Thiazide‐like diuretics, MRA, Amiloride

Site of Action, Maximum Dose, Half-Life, Onset, Bioavailability,
Pharmacology of ... , Loop diuretics ... MRA, Amiloride Site ... #Pharmacology # ... Comparison #Table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... #Pharmacology # ... nephrology #conversion ... #loop #thiazide
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal Excretion ... +2Cl- Symport (Loop ... #Renal #Excretion ... #Diuresis #Nephrology ... #Pharmacology #
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
commonly used diuretics ... medications in CKD, Cirrhotic ... Spironolactone MCW Nephrology ... #pharmacology # ... Pharmacokinetics #halflife #comparison
Causes of Hypomagnesemia
Redistribution:
 - IV glucose
 - Correction of diabetic ketoacidosis
 - IV hyperalimentation
 - Refeeding
- Alcoholism (cirrhosis ... Saline or osmotic diuresis ... disease Drugs: - Loop ... diuretics - Aminoglycosides ... medications #drugs #pharmacology
Causes of Hypomagnesemia
 • Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation,
intake: Alcoholism (cirrhosis ... Saline or osmotic diuresis ... disease • Drugs: Loop ... diuretics, Aminoglycosides ... differential #diagnosis #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
• ↓ Renal K+ Excretion ... delivery): CHF, cirrhosis ... suggests ↓ renal excretion ... (IV loop diuretic ... Treatment #potassium #nephrology