12 results
Diffuse large B cell lymphoma (DLBCL) - Management and Treatment Algorithm

By Matthew Ho, MD PhD @MatthewHoMD

#Diffuse
Diffuse large B cell ... Management and Treatment ... Algorithm By ... #Algorithm #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
older 50-70 • Malignant ... typically of B-cell ... Reed Sternberg cell ... type (B cell, T ... #oncology #diagnosis
Primary Bone Tumors - Differential Diagnosis Algorithm 

Metastatic - Most common tumour in adults
 - Breast
Bone Tumors - Differential ... Diagnosis Algorithm ... • Giant Cell ... #Diagnosis #Algorithm ... Orthopedics #Causes #Oncology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Splenomegaly - Differential ... Diagnosis Algorithm ... Infiltrative - Malignant ... Disease • Sickle Cell ... #Causes #Hematology
Genital Lesions - Differential Diagnosis Algorithm
Elevated - Vesicles:
 • Herpes simplex
Elevated - Papules / Plaques -
Genital Lesions - Differential ... Diagnosis Algorithm ... Non-infectious - Malignant ... : • Squamous cell ... #skinlesions #dermatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... common - T Cell ... ~10% - B-Cell ... Responsive to Treatment ... #algorithm
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
disorder or lymphoid malignancy ... - Lymphoid Malignancy ... rubella legionella, varicella ... malignancies - B-cell ... younger pts) Differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Consider sickle cell ... valve, vasculitis, malignant ... #workup #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... • Induce blast cell ... initiation • Differential ... Renal Failure Treatment ... #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... low white blood cell ... hematopoiesis cell ... blood count with differential ... #oncology