11 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Causes of Neutropenia ... Diagnosis Algorithm ... • Toxins • Aplastic ... Anemia • Myelodysplasia ... #Differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Presentation: • Fever • Fatigue ... #Anemia #oncology ... #hematology #diagnosis
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
- Differential ... Neoplastic / Hematologic ... • Anemia • ... Syndrome #Chronic ... #Fatigue #Differential
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Diagnosis Algorithm ... Megakaryopoiesis • Aplastic ... Anemia • Toxic ... Non-lmmune: • HELLP Syndrome ... #Causes #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5. ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
Diagnosis Algorithm ... HLH syndrome 5 ... FISH • Acquired Aplastic ... Anemia • Hypoplastic ... #Hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
- Differential ... , Kostmann syndrome ... Megaloblastic anemia-rare ... white blood cell aplasia ... diagnosis #causes #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
sweats • Extreme fatigue ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... Pure red cell aplasia ... #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Symptoms: • Fatigue ... • Aplastic Anemia ... blood count with differential ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
CML Symptoms: • Fatigue ... - infiltrates (anemia ... or functional neutropenia ... #Leukemia #Hematology ... #Oncology #Diagnosis