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diagnosis management rheumatology treatment druginduced erythematosus summary systemic antiphospholipid cerebritis cns comparison complications criteria dil hemophagocytic hlh hypercoagulable kawasaki lymphohistiocytosis
Algorithm for the Evaluation and Management of Sickle Cell Crises Clinical Manifestations and Management #Diagnosis #Management #Hematology #SickleCell
Evaluation and ... Clinical Manifestations ... Diagnosis #Management #Hematology ... Manifestations #Workup ... #Algorithm #Ddxof
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... • Evolution: ... Chronic disease
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... Chronic disease
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Cerebrovascular Disease ... autoantibodies that will cause ... (for secondary APS
Algorithm for the Evaluation of Kawasaki and Incomplete Kawasaki Disease: Diagnosis * Fever >5d * Criteria (4/5) -
Algorithm for the ... Evaluation of Kawasaki ... criteria) #Diagnosis #Peds ... #Criteria #Workup ... #Algorithm #Ddxof
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... : SLE+++, Adult-onset ... Still disease, ... Drugs, Unknown cause ... inhibitors under evaluation
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Hypercoagulable Workup ... - 1 or more clinical ... maternal chromosomal causes ... excluded Testing: • Lupus ... #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... • Immunologic Workup ... Discontinuation of causal ... #DIL #rheumatology
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