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hematology management differential leukemia syndrome chronic aplastic classification disorders hiv infections lymphocytic mds monoclonal myelodysplastic neurology syndromes workup acquired acute
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
ALL Symptoms: ... involvement • 30%: CNS ... - infiltrates (anemia ... ) CLL Symptoms: ... #Oncology #Diagnosis
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Algorithm Acute ... Lymphadenopathy, CNS ... Pelger-Huet, Macrocytic anemia ... • Lymphoid (CLL ... #Algorithm
Chronic Neutrophilic Leukemia (CNL) • Signaling Pathway • WHO Dx Critera • Risk Stratification • Treatment
Neutrophilic Leukemia (CNL ... Stratification • Treatment ... Algorithm Zhuoer ... @ZhuoerXie #CNL ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... • Neutropenia, anemia ... microglobulin Treatment ... #workup #oncology ... #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Script Signs and symptoms ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... stem cell transplant ... #treatment #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
cytopenias (usually anemia ... Allogeneic stem cell ... only curative treatment ... #Management #treatment ... #hematology #oncology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
- Differential Diagnosis ... cells per μL • Diagnosis ... Antimicrobial treatment ... #differential #diagnosis ... opportunistic #InfectiousDiseases
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... lymphoid malignancy (CLL ... of anemia include ... anemia • Cold ... #hematology #diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
• Epstein-Barr virus ... Treatment: ... • Improve the symptoms ... #oncology #hematology ... #diagnosis #management
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