15 results
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
20%) congenital infection ... disease Epstein—Barr ... #Viruses #HHV #Microbiology ... #Diagnosis #Comparison ... #Table
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... to a preceding infection ... than one after symptom ... the underlying pathophysiology ... and cauda equina TREATMENT
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... response preceding infection ... COVID 19 - Zika virus ... Diagnosis: • ... #Syndrome #diagnosis
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
DDX: • Epstein-Barr ... Viral hepatitis Diagnosis ... acquisition in which no diagnostic ... antibody test) Treatment ... Syndrome #HIV #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
ARDS to explain symptoms ... : 33% • Treatment ... : No • Treatment ... #diagnosis #comparison ... #table
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Idiopathic • Infections ... CMV) • Epstein-Barr ... aplastic anemia Treatment ... • Improve the symptoms ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
of a previously diagnosed ... Confusion, visual symptoms ... uveitis, Extraocular symptoms ... albicans • Epstein Barr ... IRIS with severe symptoms
Tongue Pathology 

Geographic tongue, fissured tongue, and hairy tongue are the most common tongue problems and
do not require treatment ... with a candidal infection ... by the Epstein-Barr ... Recognition and diagnosis ... duration, antecedent symptoms
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Pathophysiology ... : >3 symptoms, or ... : Infection (sepsis ... Renal Failure Treatment