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management hematology causes algorithm neurology oncology hemophagocytic hlh lymphohistiocytosis thrombocytosis arthritis barre cppd dermatology fever gout guillain hiv infectiousdiseases mds
Causes of Acute Onset Fever - Differential Diagnosis Algorithm Viral: • Rhinovirus • Influenza Virus • Parainfluenza
Onset Fever - Differential ... Diagnosis Algorithm ... Neuroleptic malignant syndrome ... #Differential # ... Diagnosis #Algorithm
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Diagnosis #Algorithm
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diagnosis Congenital ... Wiskott-Aldrich syndrome ... deficiency Infections ... • Epstein-Barr virus ... #Diagnosis #Hematology
Causes of Sore Throat / Rhinorrhea - Differential Diagnosis Algorithm Common viral pathogens: Rhinovirus, Coronavirus, Influenza virus,
/ Rhinorrhea - Differential ... Diagnosis Algorithm ... Head Cold Syndrome ... Infectious Mononucleosis ... #Diagnosis #Algorithm
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... risk-stratification • Risks: infection ... transformation to acute ... #Management #treatment ... #hematology #oncology
Causes of Sudden Unexpected Death in Infancy (SUDI) - Differential Diagnosis Algorithm Congenital Anomaly / Disorder: •
Infancy (SUDI) - Differential ... Diagnosis Algorithm ... Accidental* Other: • Acute ... Sudden Infant Death Syndrome ... #Causes #Peds #
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
Syndrome Acute ... Viral hepatitis Diagnosis ... acquisition in which no diagnostic ... antibody test) Treatment ... #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Myelofibrosis Infectious ... : • Acute or Chronic ... effect following treatment ... #Causes #Hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Diagnosis Secondary ... Thrombocytosis): • Acute ... infection • Solid ... Myelodysplastic syndrome ... #hematology #secondary
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