148 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... +++: Virus (EBV, ... • Autoimmune diseases ... Adult-onset Still disease ... Unknown cause Treatment
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
chronic hepatitis C virus ... (HCV) infection ... Antivirals #table #treatment ... infectiousdisease #hepatology
Bell's Palsy
Bell’s Palsy is a damage, acute weakness, or paralysis of the Facial nerve (7th CN),
associated with viral infections ... Herpes simplex virus ... - Epstein-Barr virus ... Burgdorferi (Lymes disease ... neurology #anatomy #pathophysiology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Myelofibrosis Infectious ... disorders • Celiac disease ... Non malignant hematologic ... effect following treatment ... states • Non-hematologic
Nail Clubbing - Differential Diagnosis Algorithm
Bronchopulmonary Disease
 • Bronchiectasis
 • Chronic Lung Infection
 • Lung Cancer
Bronchopulmonary Disease ... • Chronic Lung Infection ... (Crohn's Disease ... Immunodeficiency Virus ... Clubbing #Fingernail #dermatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... - B symptoms ... Etiology: - Infections ... Lymphomas • Other hematologic ... #differential #hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Congenital Diseases ... and Autoimmune Diseases ... deficiency Infections ... • Epstein-Barr virus ... Differential #Diagnosis #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... : Chronic infections
Acute Retroviral Syndrome
Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection

 •
immunodeficiency virus ... days or weeks • Virus ... • Epstein-Barr virus ... antibody test) Treatment ... ART to slow HIV disease
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Due to Viral infection ... Polyclonal - Viral Infection ... (Cold-induced symptoms ... rewarming • Symptoms ... hemolytic #anemia #hematology