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lupus sle hematology syndrome systemic differential druginduced oncology activation anemia aplastic arthritis chronic cll comparison gout hemeonc hemophagocytic hlh immune
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... life-threatening • Treatment ... #Diagnosis #Management ... #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease Treatment ... diagnosis #rheumatology ... #management
Migraine Treatment Overview • What is a Migraine? • Pathophysiology • Common Migraine Triggers • Diagnosis
Migraine Treatment ... Overview • ... Migraine Triggers • Diagnosis ... • Non-Drug Treatment ... #management #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Infections+++: Virus ... immune deficiency, Drugs ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Drug Induced Systemic Lupus Erythematosus > 100 drugs have been associated with drug-induced SLE High risk (>5%): •
Lupus Erythematosus ... for 1 year of treatment ... #pharmacology # ... #differential #diagnosis ... #rheumatology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis Summary ... Overview: chronic ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... #management #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Systemic Lupus Erythematosus ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia - Overview ... Dyskeratosis congenita • Drugs ... - Cytotoxic drugs ... aplastic anemia Treatment ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Leukemia (CLL) - Summary ... Overview: • Most ... minimal tumor burden Diagnosis ... #hemeonc #diagnosis ... #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome - Overview ... superinfection, drug ... : • Drug reaction ... active infection/drug ... #Management
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