11 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... Diagnosis: Infection ... Anaphylaxis, Acute Renal ... #diagnosis #management
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal ... , r/o infection ... sparing of the lung ... #differential # ... diagnosis #management
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Metabolic • Renal ... • Malignancy Infectious ... Epstein-Barr Virus ... Chronic Obstructive Pulmonary ... Myasthenia Gravis Pharmacologic
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... Parenchyma: • Infection ... Kaposi's sarcoma • Rheumatologic ... alveolar hemorrhage (DAH ... #Diagnosis #pulmonary
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... hemolytic anemia, PNH ... Legionnaires disease • Pulmonary ... 94 and 84% Renal ... • Toxins • Infection
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... • Shrinking lung ... #joint #pain #differential ... #diagnosis #rheumatology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Lymphadenitis, pulmonary ... leukoencephalopathy (PML ... Leishmaniasis Differential ... Inflammatory #Syndrome #Differential ... #Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... and renal abnormalities ... Vasculitis Differential ... Polyarteritis Nodosa: • PAN ... #Diagnosis #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
amyloidosis, PAH ... MALT Lymphoma • Lung ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... fibromyalgia) • Infections ... Antiribosomal P, APLA, PAC ... APLA/LAC: • Renal