38 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Infections+++: Virus ... • Autoimmune diseases ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... age, however the disease ... • Bicytopenia Treatment ... Supportive measures and treating ... #management #treatment
IDSA Recommendations for Preventing and Treating Chagas Disease (American Trypanosomiasis) in HIV-AIDS
Preventing Clinical Disease
Indication:  Individuals
Preventing and Treating ... HIV-AIDS Preventing Clinical ... and preventing clinical ... #management #opportunistic ... #infections #HIVAIDS
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... hepatitis • Pulmonary ... #diagnosis #management ... #treatment #rheumatology
Shock - Differential Diagnosis Framework
 - MAP <65. SBP <90, drop in SBP > 40
 -
- Differential Diagnosis ... , Severe Valve Disease ... • Obstructive: Pulmonary ... #criticalcare # ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Leptospirosis
Pathogen: Leptospira (interrogans, kirschneri, noguchii)
Risk Factors:
 • Occupational exposure - Farmers, ranchers, trappers, veterinarians
 • Recreational
failure • Severe pulmonary ... disease ARDS Diagnosis ... Epidemiologic exposure + clinical ... #microbiology #diagnosis ... #treatment #management
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
Infection: Coronavirus Disease ... emergency 2020-3-12 Diagnosis ... COVID19 #Cheatsheet #Diagnosis ... #Management #Summary ... #Coronavirus #CriticalCare
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
and Management ... Lung Abscess - Clinical ... Lung Abscess Management ... Lung #Abscess #pulmonary ... #treatment #diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
shunt (Type 2) Clinical ... cirrhosis • Intra-pulmonary ... perfusion scanning or pulmonary ... ) on room air Treatment ... #management #treatment